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While the study found no significant differences in the primary efficacy endpoint (time to first tolerated meal), the ipamorelin group showed reduced median time to first tolerated meal (25.3 hours versus 32.6 hours in placebo) and had fewer overall treatment-emergent adverse events (87.5% versus 94.8%)
Cole M Hughes
Retatrutide is designed to support significant weight loss by reducing appetite, improving insulin sensitivity, and influencing energy balance
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